SNCA and Parkinson disease: The pathology between GBA1 mutation carriers with PD and PD patients who do not harbor mutations in the GBA1 gene is strikingly similar – including nigrostriatal degeneration and Lewy body pathology with aggregation and phosphorylation of the alpha-synuclein (aSyn) protein (encoded by SNCA) (Blandini et al., 2018; Goker-Alpan et al., 2010; Neumann et al., 2009).