CACNA1H and Hyperglycemia: Selective in vivo knock-down of the CaV3.2 isoform of T-channels in DRG neurons reduced both hyperalgesia in vivo, and T-currents in dissociated DRG neurons of small diameter in vitro, suggesting a correlation between hyperglycemia and increased T-currents with the appearance of mechanical and thermal sensitivity in diabetic STZ-treated rats (59, 61).