According to a report by Li et al., who analyzed the expression profile of circRNAs in nonsmall cell lung cancer, a circRNA named CircNDUFB2 could inhibit nonsmall cell lung cancer progression by decreasing the stability of insulin-like growth factor 2 mRNA-binding proteins (IGF2BPs) and activating antitumor immunity [23]. The gene discussed is IGF2; the disease is lung cancer.