Authors showed that 8 weeks post injection of 5 × 1011 vg/kg of AAV2/9 driving the expression of CjCas9 and one sgRNA in mdx23 mouse model of DMD resulted in 39 ± 4% dystrophin positive fibers in mice with one base pair insertion (cytidine nucleotide) and 28 ± 6% of mice carrying 14 base pairs deletion. Here, DMD is linked to Duchenne muscular dystrophy.