Besides, our data show potential biomarkers for good GB prognosis such as lumican (Karamanou et al., 2020; Giatagana et al., 2021; Zang et al., 2021) and vitamin D (Zhang et al., 2019; Negri et al., 2020; Lo et al., 2021) (Figures 2F,G) in the identified subset of the CMA-deficient PC secretome with GB, including proteins related to anti-tumor mechanisms and immune responses (Figure 2B). Here, LUM is linked to neoplasm.