SLC1A5 and pachyonychia congenita: Especially in the GSE43795 dataset, SLC1A5 was upregulated in two subtypes of PC, namely, solid-pseudopapillary neoplasm of pancreas (SPN) and pancreatic ductal adenocarcinoma (PCA), but was downregulated in the neuroendocrine tumor (NET) (Figure 2L).