SLC7A11, a cystine/glutamate antiporter, not only enhances cervical cancer progression by circEPSTI1-miR-375-SLC7A11 axis (Wu et al., 2021) but also serves as an unfavorable prognostic biomarker in renal carcinoma (Xu et al., 2021a). This evidence concerns the gene SLC7A11 and renal carcinoma.