HMMR and hepatocellular carcinoma: Consistent with those studies, the cell cycle signature composed of 13 cell cycle-related genes (TICRR, SPDL1, SGO1, HJURP, CENPA, GINS1, EZH2, BRSK1, NUF2, PLK1, HMMR, E2F2, and CDCA8) possessed superior specificity and sensitivity in predicting the OS of HCC patients.