At the protein expression level, western blot results showed that the expression levels of PGC1α, NRF1, GXP4, catalase, SOD, p-ERK, UCP2, and Bcl2 were inhibited by treatment with PCOS and erastin but these inhibitory effects were reversed by treatment with CRY or CRY+ferrostatin-1 (Figure 9(f)). The gene discussed is NRF1; the disease is polycystic ovary syndrome.