As shown in Table 5, DRB1*03:01∼DQB1*02:01 + DRB1*04:02/05∼DQB1*03:02 0.104 vs. 0.006, OR = 25.03 (8.23–97.20, p = 2.6 × 10−10) followed by the homozygous DRB1*03:01∼DQB1*02:01 + DRB1*03:01∼DQB1*02:01 [0.094 vs. 0.01, OR = 8.72 (3.17–25.32), p = 3.18 × 10−8] were associated with heightened risk for T1D. This evidence concerns the gene HLA-DRB1 and type 1 diabetes mellitus.