Lv et al. have found that dietary genistein supplementation in feed inhibited fatty acid synthesis and enhanced β-oxidation in the livers of layers with fatty liver syndrome through the PPAR–ACAD pathways, thereby alleviating fat deposition and lipid metabolism disorder, resulting in significant improvement in the laying rate poultry (Lv et al., 2018). The gene discussed is PPARA; the disease is Disorder of lipid metabolism.