In addition, the associations between CHD and blood-based hypermethylation of several genes, such as FOXP3 (forkhead box P3), ABCG1 (ATP binding cassette subfamily G member 1) and GALNT2 (polypeptide N-acetylgalactosaminyltransferase 2), and hypomethylation of IL-6 (interleukin 6) have been reported (Jia et al., 2013; Peng et al., 2014; Zuo et al., 2016). Here, IL6 is linked to coronary artery disorder.