CALM2 and chronic rhinosinusitis with nasal polyps: Expression of the carbohydrate metabolism-associated gene ALDH3A1 (Figure 4O), the antimicrobial protein clusterin (CLU) (Figure 4P), and calmodulin 2 (CALM2) (Figure 4Q), a calcium-binding protein involved in mediating ciliary beat responses in the human nasal epithelium (34), were also significantly reduced in cells from AERD as compared to CRSwNP patients.