Comparing the epithelial cell cluster in AERD and CRSwNP patients (Figure 4A), we observed a trend towards, but not a significant, increase in the T2-associated alarmins thymic stromal lymphopoietin TSLP and IL33 in AERD using scRNA analysis (Figures 4B, C). The gene discussed is IL33; the disease is chronic rhinosinusitis with nasal polyps.