In summary, we could show that within the murine peritoneal cavity, the peritoneal membrane lined by PeM cells expresses stable levels of cell adhesion markers VCAM-1 and ICAM-1 under steady state and following cure of a primary infection, and significantly downregulates the gene expression of both markers in response to a challenge nematode infection. The gene discussed is ICAM1; the disease is Nematoda infectious disease.