Furthermore, considering the initial expansion of peritoneal Th2 cells during early recall responses at 3 days post-challenge in the PEC only, and the contrasting later expansion of Gata3+ cells in the gut-draining lymph nodes by 14 days post-challenge infection, our findings therefore suggest that the host peritoneal compartment participates in and supports specifically early recall responses to the enteric parasite H. polygyrus. This evidence concerns the gene GATA3 and infection.