One hnRNP (hnRNPD) and two histone (H2BC and H3A) IgGs were in the top 500 highest AAbs (as measured by mean intensity after log2 transformation), while most other hnRNPs, histones, GPI, SSAs, Sm, and other commonly expressed autoimmune-disease associated autoantibodies did not have high mean intensities. Here, HNRNPD is linked to autoimmune disease.