Together with TOP/FOP-flash assays, which confirmed CENPK promoted Wnt signaling (Fig. 5a), and previous studies that showed SOX6 activated p53 signaling and inactivated Wnt signaling [27] while also suppressing cervical cancer progression [28], we selected SOX6 as a candidate protein interaction partner of CENPK. Here, SOX6 is linked to cervical cancer.