SIRT1 and non-alcoholic fatty liver: Although the therapeutic effects of folic acid against a rat model of high-fat diet-induced NAFL was previously investigated, to the best of our knowledge, this is the first report linking the probable molecular effect of folic acid with the the expression of mature miR-21, -34a, and -122 as well as their targeted genes HBP1, SIRT1, and SREBP-1c.