Whereas B-cell changes, such as the reduction of transitional CD24highCD38high cells, are largely restored in convalescent patients, T cells from recovered patients continue to show persistence of cytotoxic programming of CD8+ and elevated production of type 1 cytokines and IL-17 (31), which is known to be a driver of inflammatory reactions and autoimmunity (32). The gene discussed is CD8A; the disease is Autoimmunity.