PGP and neoplasm: These proteins are ATP dependent transporters that extrude chemotherapeutic agents reducing their intracellular concentration; consequently, the effectiveness of anticancer drugs is weakened.[4] In humans, the transporter proteins mainly associated with MDR are P‐glycoprotein (P‐gp, ABCB1), Multidrug‐Resistance‐associated Protein‐1 (MRP1, ABCC1), and Breast Cancer Resistance Protein (BCRP, ABCG2) which are overexpressed in several resistant tumours.[5, 6]