Our previous studies demonstrated that high expression of Glut‐1 is associated with radioresistance in laryngeal carcinoma.20, 21, 22 Additionally, we revealed a significant correlation between HIF‐1α and Glut‐1 in patients with laryngeal carcinoma.10, 14 Therefore, we presume that HIF‐1α and Glut‐1 act synergistically to induce radioresistance in laryngeal carcinoma. This evidence concerns the gene HIF1A and laryngeal carcinoma.