With the arrays of microbes identified in fermented fish and vegetable products (although studies on fermented fish peptides are few), researchers can enlist important molecules associated with anti-microbial, anti-obesity, anti-oxidative, anti-hypertensive, even protein molecules that inhibit the activities of ACE- a host receptor that viral agents attach for host entry and replication. Here, ACE is linked to obesity due to melanocortin 4 receptor deficiency.