We then established dose–response curves for the effect of BA on hyperglycemia-mediated oxidative stress and inflammation, and the results showed that BA (20 μM) treatment significantly ameliorated hyperglycemia (HG)-mediated increased MG formation (Figure 1h) and ROS formation (Figure 1i), as well as hyperglycemia (HG)-mediated decreased Nrf2 activity (Figure 1j) and increased NFκB p65 activity (Figure 1k). The gene discussed is NFE2L2; the disease is Hyperglycemia.