LV: left ventricular; IOC: iron overload cardiomyopathy; HFE: hereditary hemochromatosis; LGE: late gadolinium enhancement; alpha-Gal A: alpha-galactosidase A; GI: gastrointestinal; AV: atrioventricular; RCM: restricted cardiomyopathy. Here, GLA is linked to restrictive cardiomyopathy.