ALKBH5 and malignant glioma: The expression level of the ALKBH5 gene is positively correlated with the stage of ovarian cancer, and it can inhibit the autophagy of ovarian cancer through the mTOR pathway to promote the proliferation and invasion of ovarian cancer cells.34 Furthermore, a high level of ALKBH5 is an adverse prognostic factors in patients with malignant glioma.