SAV1 and Miyoshi myopathy: Then, RNA sequencing analysis showed that 24 genes were downregulated in the “ALKBH5--specific gene” group compared with control MM cells, and 120 genes were downregulated in the “NC-specific gene” group compared with control MM cells, and SAV1 gene was selected among the mutually downregulated genes in both groups (Figure 4E and 4F).