ALKBH5 and central nervous system cancer: ALKBH5 can stabilize the expression of FOXM1 mRNA by eliminating the m6A modification of FOXM1 precursor RNA and enhance the self-renewal ability of glioma stem cells, thereby promoting the progression of malignant glioma.35 However, ALKBH5 inhibited pancreatic cancer motility and was positively associated with the prognosis of pancreatic cancer patients by reducing the methylation of the kcnk15-as1 lncRNA.36 Our research supported the supposition that ALKBH5 plays a carcinogenic role in MM progression, which is consistent with most studies.