Additionally, the DNA methylation level of cg23487201, whose DNA methylation level was most negatively correlated with APCDD1L-AS1 expression based on TCGA-KIRC data, was also higher in ccRCC compared with AN tissue based on the data from GSE105260 (Fig. 5A). Here, APCDD1L is linked to nonpapillary renal cell carcinoma.