To explore the correlation between MGP and the growth and metastasis of CRC in vivo, the sh-MGP and sh-NC groups were injected MC38 and CT26 cells into the spleen of C57BL/6 and BALB/C mice, respectively, followed by αPD1 injection to assess the hepatic metastatic capacity of these cells (Figure 10A). The gene discussed is MGP; the disease is colorectal carcinoma.