KEGG pathway analyses revealed that P. acnes-induced and Bmal1-regulated inflammations were associated with activation of NF-κB and NF-κB-related signaling pathways (such as tuberculosis, rheumatoid arthritis, leishmaniasis, inflammatory bowel disease, epstein-barr virus infection, and asthma) (Fig. 5C). This evidence concerns the gene BMAL1 and rheumatoid arthritis.