Therefore, to resolve the underlying mechanism by which ATRAP promotes breast cancer progression, we used the BioGRID database (https://thebiogrid.org/) to explore potential ATRAP interaction partners, which revealed a variety of candidate proteins, among which we selected PBX3 for closer scrutiny based on its reported function in promoting tumor migration and invasion 30, 31 (Figure 4A and Table S4). Here, AGTRAP is linked to neoplasm.