NDUFS2 and nonpapillary renal cell carcinoma: In addition, using the TCGA-KIRC data, we found that DNUFS2 expression was decreased in ccRCC, and lower NDUFS2 expression was associated with worse pathological characteristics, including T3/T4, G3/G4 and Stage III/IV, and predicted a poor prognosis of ccRCC patients (Fig. 5G).