MYCNUT and glioblastoma: Several genes were almost confirmed to regulate differentiation (GFAP, OLIG3, BMPR1B, MYCNUT, DLX5, DNER) and to encode for RTK activity, critical in the oncogenesis of GBM, including NTRK, REPS2, ERBB4 and DOK5, confirming an “hybrid” astrocyte-like/mesenchymal-like (AC-like/MES-like) state within this subset of GSCs [58].