Compared to patients with lower plasma sTREM2 levels, those with higher sTREM2 were more likely to be older and female; have higher admission NIHSS score, galectin-3, total cholesterol, low-density lipoprotein and high-density lipoprotein cholesterol; have higher prevalence of embolic stroke, history of coronary heart disease, history of antihypertensive and lipid-lowering medications use; have lower baseline diastolic BP; have lower prevalence of cigarette smoking, alcohol drinking and family history of stroke (Table 1). The gene discussed is LGALS3; the disease is stroke disorder.