The expression levels of the proinflammatory cytokines TNF-α and IL-6 were assessed via immunohistochemistry, and the expression levels of TNF-α and IL-6 in the pancreatic islet cells of T2DM mice were abrogated via hUC-MSC infusion in the UCMSC and UCMSC/Mel groups (Fig. 4d, e). This evidence concerns the gene TNF and type 2 diabetes mellitus.