CDH2 and neoplasm: Cervical histochemical results showed that the expression of its ligands E, N-cadherin in CIN II–III was significantly increased, and E-Cadherin was also increased in CIN I. It may be noted that even though the expression of E-cadherin is reduced in most tumor studies to increase cell invasiveness, correlation studies showed that some tumors may paradoxically use KLRG1-cadherin to evade immune surveillance.