Frequencies of Tc1 cells were significantly higher in SF compared with PB in both the PD-1 inhibitor arthritis group and the combined ICI arthritis groups (PD-1 inhibitor arthritis; SF Tc1 vs. PB Tc1; 71.7 ± 19.8 vs. 26.8 ± 13.5%; P = 0.04) (Combined ICI arthritis; SF Tc1 vs. PB Tc1; 63.2 ± 22.4 vs. 29.3 ± 17.9%; P = 0.0007). Here, PDCD1 is linked to arthritic joint disease.