To investigate the anti-myeloma effect of specific T cells activated by mDCs loaded with gamma-irradiated cancer cells (ARH77 or IM9), we performed an indirect cytotoxic IFN-γ ELIspot assay to track IFN-γ production by T cells, CIK cells, and NK cells, along with a CD107a degranulation assay. This evidence concerns the gene IFNG and plasma cell myeloma.