KLF11 and renal fibrosis: Based on observations that KLF11 deficiency may increase inflammation in non-renal experimental systems [11], we sought to test the hypothesis that KLF11 deficiency exacerbates renal damage in the murine Unilateral Ureteral Obstruction (UUO) model of renal fibrosis [12] by promoting a pro-inflammatory and pro-fibrotic phenotype.