Additional gross lesions noted in some subjects included adrenomegaly (D5-CTRL, D5-RDV-1, D5-RDV-2, D6-CTRL, D6-RDV-1, D6-RDV-2, D6-RDV-3, D6-RDV-4, D6-RDV-5, D6-MBP-2, D6-MBP-4, D6-MBP-5, and D6-COMB-5), petechial skin rash or edema (D5-CTRL, D5-RDV-2, D6-CTRL, D6-RDV-1, D6-RDV-2, D6-RDV-3, D6-RDV-4, D6-RDV-5, D6-MBP-2, D6-MBP-4, D6-MBP-5, and D6-COMB-5), intestinal hemorrhage (D6-CTRL, D6-RDV-1, D6-RDV-4, D6-RDV-5, D6-MBP-2, D6-MBP-4, and D6-COMB-5), testicular hemorrhage (D5-RDV-1 and D6-RDV-3), ascites (D5-RDV-1, D6-CTRL, and D6-COMB-5), and pleural effusion (D6-CTRL). The gene discussed is MBP; the disease is Ascites.