ABCF2 and renal cell carcinoma: In conclusion, circNOLC1 is increased during the progression of renal cell carcinoma; CircEHD2 inhibition reduces the resistance of RCC to SU; miR-4731-5p directly targets the circEHD2 and ABCF2 to arrest the establishment of renal cell carcinoma, and ABCF2 reverses the inhibitor effect of circEHD2 on SU resistance of RCC.