The Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analysis indicated that the upregulated genes upon ASFV-ΔA137R infection were involved in the IFN signaling pathway, such as cytosolic DNA-sensing, JAK-STAT, and Toll-like receptor (TLR) signaling pathways (Fig. 1F). Here, IFNA1 is linked to infection.