Table 2 shows and compares the mean values for the hormonal determinations (FSH, LH, estradiol, ACTH, cortisol, 17-OH-P, DHE-S, androstendiona, T and FT) in prepubertal and early-puberty subgroups in accordance to BMI status (control and obesity groups). The gene discussed is POMC; the disease is obesity due to melanocortin 4 receptor deficiency.