GPT and arthropathy: The reported grade 3 AEs include increased γ-GTP in 4 (18.2%) patients, decreased lymphocyte count in 2 (9.1%) patients, and gingival infections, diabetes mellitus, hyperglycaemia, hypertension, duodenal ulcer, nausea, acute cholangitis, joint effusion, increased ALT, increased AST and decreased white blood cell count each in 1 (4.5%) patient (Table 3).