The protective effect of rs72613567T>TA in HSD17B13 on the diagnosis of NAFLD remained after adjusting for the presence of rs738409C>G in PNPLA3, in addition to age, sex, and BMI z score (OR, 0.74; 95% CI, 0.57–0.95). Here, PNPLA3 is linked to metabolic dysfunction-associated steatotic liver disease.