Pathways in cancer, hepatitis B, endocrine resistance, proteoglycans in cancer, AGE-RAGE signaling pathway in diabetes complications, PI3K-Akt signaling pathway, apoptosis, platinum drug resistance, TNF signaling pathway, IL-17 signaling pathway, progesterone-mediated oocyte maturation, and the prolactin signaling pathway were included in Fig. 5. The gene discussed is AKT1; the disease is hepatitis B virus infection.