ESR1 and ovarian carcinoma: Gene targets can be screened from the color of node size: PTGS1, TP53, PTGS2, AKT1, MAPK1, JUN, AR, EGFR, ESR1, etc. These can be considered to be the core targets in the target interaction network of the Danshen-Guizhi drug pair for the treatment of ovarian cancer (Fig. 2).