AFP and hepatocellular carcinoma: The prognostic factors of hepatocellular cancer include demographic characteristics of patients (age, gender, accompanying hepatitis B, C infections, degree of cirrhosis), tumor-related factors (tumor size, tumor multifocality or presence of portal vein thrombosis, AFP values), and liver damage indicators that reflect microenvironment of the liver or tumor such as GGT, ALT, AST, and bilirubin [3–6].