For example, the expression of different cytokines (CCL2/3/4/5), co-stimulatory genes (CD27, TNFRSF4 [HVEM], TNFRSF14 [OX40], TNFRSF25 [DR3]), and IFNγ response genes (e.g., B2M, TAP1, HLA molecules) were upregulated in different non-leukemic NK-cells, monocytes, and B-cell clusters in comparison with healthy controls (Fig. 5a), other cancers (Supplementary Fig. 14a), and patients with blood cancers (Supplementary Fig 14b, Supplementary Data 2). This evidence concerns the gene B2M and hematopoietic and lymphoid system neoplasm.