After clustering (Fig. 4a, Supplementary Fig. 12a–c), we observed that, in comparison with the other cancers, the proportion of conventional dendritic cells (cDCs) (P < 0.01 and Padj = 0.052, Benjamini-Hochberg corrected Mann-Whitney test) and naïve B-cells (P < 0.05 and Padj = 0.16) were reduced, and the proportion of mature CD4+ TEM-cells (clusters 2 and 13, both P < 0.01 and Padj = 0.052) was increased in T-LGLL (Fig. 4b, Supplementary Fig. 13a–b). Here, CD4 is linked to cancer.