CD8A and rheumatoid arthritis: Therefore, we compared the clonality of the non-leukemic CD8+ T cells in T-LGLL to CD8+ sorted healthy and RA samples24,32 and found that the non-leukemic CD8+ T cells in patients with T-LGLL had a more restricted TCR repertoire than patients with RA (P < 0.01, Mann-Whitney test) and healthy controls (P < 0.05), latter of which was validated in the MNC-cohort (P < 0.0001, Fig. 4e).