CD8A and T-cell large granular lymphocyte leukemia: Despite similarities with the clonally expanded CD8+ T cells (defined as at least two cells with identical TCR) from the healthy controls, the clonally expanded CD8+ T cells from T-LGLL patients also had unique T-LGLL-specific characteristics, and they were overrepresented in several CD8+ T cell clusters (Supplementary Fig. 3e).