PTPRC and T-cell large granular lymphocyte leukemia: To gain an unsupervised view of the immune system in T-LGLL, we analyzed over 150,000 flow cytometry-sorted CD45+ blood mononuclear cells (Supplementary Fig. 1a) from 11 T-LGLL samples from nine individuals and six age-matched healthy controls with scRNA+TCRαβ-seq (10X Genomics, Supplementary Data 1).