TF and cardiovascular disorder: Moreover, contrary to the iron-heart hypothesis, several biomarkers of iron status like serum iron or transferrin saturation have shown robust inverse associations between iron concentrations and cardiovascular risk.19 Therefore, the previous data on relationship between the iron body sources and cardiovascular disease might be masked with other aspects of the lifestyle that increase the risk for cardiovascular diseases.20 Red meat might exert its negative effect on cardiovascular events through other mechanisms than the irons suspected pathological effects.