The results proved that, whether in NPC tissues (Fig. 1E) or NPC cell lines (Fig. 1F), a high methylation level at this region was observed in MFSD4A. Based on the above findings, we concluded that the promoter region of MFSD4A was hypermethylated in NPC, compared with that in normal tissues. Here, SLC60A1 is linked to nasopharyngeal carcinoma.