SH3PXD2A and lung cancer: To explore the biological functions of SH3PXD2A-AS1 in lung cancer cells, we first examined SH3PXD2A-AS1 expression in the immortalised normal human lung epithelial cell line BEAS-2B and a series of lung cancer cell lines, including A549, H1299, H292 and H23, by qRT-PCR (Fig. 2A).