In the present study, we compared expression levels of phototransduction-related genes (blue opsin, rhodopsin, S-antigen, guanine nucleotide-binding protein G(t) subunit alpha-1 and 2 (GNAT1, GNAT2)) by qRT-PCR and gene expression profiles by microarray in photoreceptor-like cells from EYS-RP patients with those from age-matched normal volunteers. Here, GNAT1 is linked to retinitis pigmentosa 1.