In an attempt to evaluate the functional consequences of these changes in cell surface marker expression particularly on the T cell response, we determined the levels of central T cell cytokines, such as IFN-y, a Th-1 cytokine, IL-10, a Th-2 cytokine, known to be immunosuppressive in the setting of surgery-induced infections, and IL-6, a proinflammatory mediator [12]. The gene discussed is IL10; the disease is infection.