It has been reported that phosphorylation of Drp1 at S616 by Pink1 induces mitophagy-independent mitochondrial fission in somatic HEK293 cells [20], and Redox oxidative species (ROS)-mediated phosphorylation of Drp1S616 promotes mitochondrial fission in triple-negative breast cancer cells [21]. The gene discussed is PINK1; the disease is triple-negative breast carcinoma.